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Aluminum Zirconium Octachlorohydrex Gly

Also known as: Aluminum zirconium octachlorohydrex glycine complex

Low concern

Recognized by the FDA as a safe and effective antiperspirant active in OTC monograph products. Long-standing public concerns linking antiperspirants to breast cancer and Alzheimer's disease are not supported by current evidence reviews.

What it is

An aluminum-zirconium complex stabilized with glycine, used as the active ingredient in antiperspirants to reduce sweat.

Not a food ingredient; functions as an antiperspirant active in cosmetic/OTC drug products by forming a temporary plug in sweat ducts.

Why it's flagged

Skin irritation: Can cause irritation or contact dermatitis in some users.

Regulatory status

United States — FDA

OTC antiperspirant active (21 CFR 350)

European Union — EFSA

Not applicable (cosmetic ingredient)

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