Adenosine
Adenosine occurs naturally in all human cells and in many foods. As a topical cosmetic ingredient it is widely used at low concentrations (0.04–0.1%) and considered safe.
What it is
Adenosine, a naturally occurring purine nucleoside (adenine + ribose) found in all living cells.
Cosmetic skin-conditioning agent; used in supplements; also occurs naturally in foods.
Why it's flagged
- pharmacological cardiac activity at IV doses (not a concern from food/cosmetic levels)
What regulators actually say
"Adenosine monophosphate (AMP) received FDA acknowledgement of its GRAS (generally recognized as safe) status... a natural compound that may be used in food and beverage products and in oral pharmaceuticals to help block the bitter taste."
Regulatory status
United States — FDA
AMP affirmed GRAS as flavor modifier; adenosine itself in supplements is a dietary ingredient
European Union — EFSA
Cosmetic ingredient; permitted as supplement subject to national rules
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