Acetyl Tyrosine
N-acetyl-tyrosine is used in supplements and IV nutrition. Studies suggest poor in vivo conversion to free tyrosine in humans, limiting bioavailability.
What it is
N-acetyl-L-tyrosine, an acetylated form of the amino acid tyrosine, more water-soluble than tyrosine itself.
Used in dietary supplements and parenteral nutrition; generally not a typical food additive.
Why it's flagged
- poor conversion to free tyrosine in humans
- limited long-term safety data
What regulators actually say
"N-acetyl-L-tyrosine is poorly hydrolyzed in vivo and is largely excreted unchanged in the urine, raising questions about its efficacy as a tyrosine source."
"Dietary supplements are regulated under the Dietary Supplement Health and Education Act (DSHEA) of 1994."
Regulatory status
United States — FDA
Sold as dietary supplement under DSHEA; not GRAS as food additive
European Union — EFSA
Used in parenteral nutrition; not a general food additive
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